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R&D has a specific statutory meaning for the purpose of the tax credits that is not the same as the commercial meaning of R&D.
For the purpose of the tax credits R&D takes place where a project seeks to achieve an advance in overall knowledge or capability in a field of science or technology. It is not sufficient to achieve an advance in a company's own state of knowledge or capability alone.
Only revenue type expenditure is included in the tax credit relief - relief for R&D capital expenditure may be available under the R&D capital allowances scheme [insert link to R&D capital allowances page].
Read about the meaning of R&D for tax purposes at the HMRC website
The definition of a SME is that used by the European Commission. Briefly, an SME is a company with fewer than 250 employees, and either annual turnover not exceeding €50M or a balance sheet total not exceeding €43M, and which is not part of a larger enterprise that would fail these tests.

A large company is any company that does not meet the SME definition. However, there are some cases where an SME doesn't qualify to claim under the SME scheme but can obtain relief under the Large Company scheme.

An SME can receive a tax deduction in its corporation tax return amounting to 150% of the qualifying R&D expenditure.
If the deduction adds to or creates a tax loss then the loss can be surrendered in exchange for a cash payment of up to 16% of the loss.
The relief is subject to a number of conditions the main ones being:
- The company must have annual qualifying R&D expenditure of at least £10,000 (until 27 September 2003, £25,000)
- Any Intellectual Property (IP) arising from the R&D must belong to the company
- The company must not be receiving any "notified state aid" for the project which comprises most UK Government and EU grants and awards
- The R&D project must not be funded by someone else and
- The R&D must not have been contracted from another business.
- The R&D being contracted out by another business
- The R&D being funded by someone else or
- Receiving notified state aid for the project
- Inadequate planning of the recording of R&D expenses
- No cost v benefit analysis being carried-out prior to applying for grants or awards
- Failing to qualify as SME's due to the terms of agreements with VCs or other funders
- Lack of understanding of the rules regarding sub-contracted R&D
- The lack of a proper submission letter or advance discussion with HMRC
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